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KMID : 0614620160680030132
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Korean Journal of Gastroenterology
2016 Volume.68 No. 3 p.132 ~ p.137
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Current Status of Translational Research on Functional Dyspepsia
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Park Jae-Ho
Kim Jong-Wook
Park Jong-Kyu
Shin Cheol-Min
Jung Kee-Wook
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Abstract
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Functional dyspepsia (FD) has a diverse pathophysiology and treatment is difficult. Translational research to understand its pathophysiology is underway. Hormonal factors, including ghrelin, seem promising, offering an understanding of appetite and eating. Functional MRI brain study can expand our knowledge of the brain-gut axis. Finally, immune systems research, including mast cells, can help with comprehensive understanding of FD. The clinical approaches based on these translational research projects are necessary to improve understanding of FD, leading to more effective treatment.
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KEYWORD
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Functional dyspepsia, Translational medical research
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